Can I Use a PCIe NVMe SSD in a PCIe Motherboard Slot?

NVMe vs : What's the difference? Enable Sysadmin nvme m2 slot Non-Volatile Memory Express drives attach to the Peripheral Component Interconnect Express slot directly on a motherboard instead nvme m2 ssd slot My small Kingston A2000 drive works and boots in either nvme slot The P3 works only in the first slot I've checked

nvme gen 4 in gen 3 slot PC Components · Form Factor: 2280 · Interface: PCI-Express x4, NVMe · Total Capacity: 256GB* · Warranty: Limited 5-year or 300TBW · Sequential Read